Noise Scaling Effects on Calibration of Tabular Foundation Models in TabBench Tasks

Abstract

Abstract: Generative AI foundation models offer transformative potential for processing structured biological data, particularly in single-cell RNA sequencing, where datasets are rapidly scaling toward billions of cells. We propose the use of agentic foundation models with real-time web search to automate the labeling of experimental data, achieving up to 82.5\% accuracy. This addresses a key bottleneck in supervised learning for structured omics data by increasing annotation throughput without manual curation and human error. Our approach enables the development of virtual cell foundation models capable

Research Question

How does noise scale in synthetic tabular data generation influence the calibration of tabular foundation models as measured by expected calibration error across diverse TabBench tasks?

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